MAST-CELL HETEROGENEITY - PROTEIN-COMPOSITION, BIOSYNTHESIS AND MESSENGER-RNA CHARACTERIZATION

被引：10

作者：

BENYON, RC

IMAI, T

ABE, T

BEFUS, D

机构：

[1] UNIV CALGARY,HLTH SCI CTR,IMMUNOL SCI RES GRP,3330 HOSP DR NW,CALGARY T2N 4N1,ALBERTA,CANADA

[2] JIKEI UNIV,DEPT OTORHINOLARYNGOL,TOKYO 105,JAPAN

[3] AKITA UNIV,SCH MED,DEPT PARASITOL,AKITA 010,JAPAN

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1991年 / 94卷 / 1-4期

关键词：

D O I：

10.1159/000235364

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Proteins of rat peritoneal mast cells (PMC), rat intestinal mast cells (IMMC) and human skin mast cells (SMC) were compared by two-dimensional electrophoresis. PMC and IMMC had many similarities in distribution of their neutral/acidic proteins but marked differences in the more abundant, granule-associated basic proteins. SMC proteins showed a unique distribution. Distributions of the products of in vitro translation of PMC and IMMC RNA were different from those of proteins isolated directly from these cells which, together with results of pulse-chase labelling experiments, shows evidence for processing of certain mast cell proteins including rat mast cell proteases I and II.

引用

页码：218 / 219

页数：2

共 5 条

[1] MAST-CELL HETEROGENEITY - 2-DIMENSIONAL GEL-ELECTROPHORETIC ANALYSES OF RAT PERITONEAL AND INTESTINAL MUCOSAL MAST-CELLS [J].