HEREDITARY HYPOTRICHOSIS OF THE SCALP

被引:13
作者
HESS, RO
UNO, H
机构
[1] WISCONSIN REG PRIMATE RES CTR,MADISON,WI
[2] DEPT PATHOL & LAB MED,MADISON,WI
来源
AMERICAN JOURNAL OF MEDICAL GENETICS | 1991年 / 39卷 / 02期
关键词
HYPOTRICHOSIS SIMPLEX; BALDNESS; AUTOSOMAL DOMINANT INHERITANCE;
D O I
10.1002/ajmg.1320390202
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Hypotrichosis of the scalp was found in 4 individuals of a 6-generation Caucasian family. This congenital phenomenon is a rather rare subtype of hereditary hypotrichosis and affects only scalp hair. The hairs of the scalp were generally sparse and short vellus type from childhood and thinned progressively with age. Morphologic studies showed poor imbrication of cuticles and dysplastic bulbar structure of the anagen follicles. The density of hair follicles per/cm2 area was comparatively lower than that of normal individuals. The genealogical study and histomorphometrical findings of this autosomal dominant trait are discussed along with previously reported causes of hypotrichosis.
引用
收藏
页码:125 / 129
页数:5
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