HYPONATREMIC COMA UNDER OXCARBAZEPINE THERAPY

被引：43

作者：

STEINHOFF, BJ ^{[1
]}

STOLL, KD ^{[1
]}

STODIECK, SRG ^{[1
]}

PAULUS, W ^{[1
]}

机构：

[1] CIBA GEIGY MED,FRANKFURT,GERMANY

来源：

EPILEPSY RESEARCH | 1992年 / 11卷 / 01期

关键词：

OXCARBAZEPINE; HYPONATREMIC COMA;

D O I：

10.1016/0920-1211(92)90023-M

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Oxcarbazepine (OXC) is considered to be a promising new antiepileptic drug with similar efficacy and better tolerability compared to carbamazepine (CBZ). However, hyponatremia is supposed to occur even more often than with CBZ. We report on a patient who developed hyponatremic coma under OXC with a serum sodium level of 115 mmol/l, the second published case of OXC-induced hyponatremia with serious clinical adverse effects.

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页码：67 / 70

页数：4

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