GREATER AMOUNT OF HCV-RNA IN TEARS COMPARED TO BLOOD

被引：27

作者：

FEUCHT, HH

POLYWKA, S

ZOLLNER, B

LAUFS, R

机构：

[1] Institut für Medizinische Mikrobiologie und Immunologie, Universitätskrankenhaus Eppendorf (UKE), Martinistr. 52

来源：

MICROBIOLOGY AND IMMUNOLOGY | 1994年 / 38卷 / 02期

关键词：

HEPATITIS C VIRUS (HCV); POLYMERASE CHAIN REACTION (PCR); TEAR FLUID;

D O I：

10.1111/j.1348-0421.1994.tb01758.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Plasma, tear fluid and swabs from eye, nose and pharynx of 33 patients were examined for presence of hepatitis C virus (HCV) RNA by polymerase chain reaction (PCR). Ail samples from plasma, tear fluid and eyeswabs were found to show a positive reaction in HCV-RNA PCR. Remarkably, we regularly found greater amounts of amplification products in tear fluid and eyeswabs compared to plasma using the same conditions for sample preparation.

引用

页码：157 / 158

页数：2

共 6 条

[1]

Erlich H. A., 1990, PCR PROTOCOLS, P261

[2]

FUJIKAWA LS, 1985, LANCET, V2, P529

[3] CHARACTERIZATION OF THE TERMINAL REGIONS OF HEPATITIS-C VIRAL-RNA - IDENTIFICATION OF CONSERVED SEQUENCES IN THE 5' UNTRANSLATED REGION AND POLY(A) TAILS AT THE 3' END [J].

HAN, JH ;

SHYAMALA, V ;

RICHMAN, KH ;

BRAUER, MJ ;

IRVINE, B ;

URDEA, MS ;

TEKAMPOLSON, P ;

KUO, G ;

CHOO, QL ;

HOUGHTON, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (05) :1711-1715

[4] DETECTION OF HCV RNA IN SALIVA, URINE, SEMINAL FLUID, AND ASCITES [J].

LIOU, TC ;

CHANG, TT ;

YOUNG, KC ;

LIN, XZ ;

LIN, CY ;

WU, HL .

JOURNAL OF MEDICAL VIROLOGY, 1992, 37 (03) :197-202

[5] TYPING OF HEPATITIS-C VIRUS GENOMES BY RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISM [J].

NAKAO, T ;

ENOMOTO, N ;

TAKADA, N ;

TAKADA, A ;

DATE, T .

JOURNAL OF GENERAL VIROLOGY, 1991, 72 :2105-2112

[6] CLOSE CORRELATION BETWEEN HEPATITIS-C VIRUS SEROLOGY AND POLYMERASE CHAIN-REACTION IN CHRONICALLY INFECTED PATIENTS [J].

REUTER, D ;

POLYWKA, S ;

ISKE, L ;

FEUCHT, HH ;

LAUFS, R .

INFECTION, 1992, 20 (06) :320-323

← 1 →