A NOVEL MICROMANIPULATION TECHNIQUE FOR MEASURING THE BURSTING STRENGTH OF SINGLE MAMMALIAN-CELLS

被引：85

作者：

ZHANG, Z

FERENCZI, MA

LUSH, AC

THOMAS, CR

机构：

[1] UNIV BIRMINGHAM,SCH CHEM ENGN,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

[2] BRIT BIOTECHNOL LTD,OXFORD OX4 5LY,ENGLAND

[3] NATL INST MED RES,LONDON NW7 1AA,ENGLAND

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 1991年 / 36卷 / 02期

关键词：

D O I：

10.1007/BF00164421

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Information about the bursting strength of animal cells is essential if the mechanisms of cell damage in bioreactors are to be understood, and if cell mechanical properties are ever to be related to cell structure and physiology. We have developed a novel cell compression technique that makes it possible to directly measure the bursting strength of single mammalian cells, and to infer information about cell mechanical properties.

引用

页码：208 / 210

页数：3

共 10 条

[1] MECHANISMS AND KINETICS OF MONOCLONAL-ANTIBODY SYNTHESIS AND SECRETION IN SYNCHRONOUS AND ASYNCHRONOUS HYBRIDOMA CELL-CULTURES [J].