SPECTROPHOTOMETRIC DETERMINATION OF RUTIN IN PHARMACEUTICAL PREPARATIONS USING 3-METHYLBENZTHIAZOLINONE-2-HYDRAZONE

被引：16

作者：

LAVANYA, K ^{[1
]}

BAGGI, TR ^{[1
]}

机构：

[1] BUR POLICE RES & DEV,MHA,CENT FORENS SCI LAB,OU CAMPUS,HYDERABAD 500013,INDIA

来源：

MICROCHEMICAL JOURNAL | 1990年 / 41卷 / 02期

关键词：

D O I：

10.1016/0026-265X(90)90110-Q

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A spectrophotometric method for the determination of rutin has been developed. The method is based on the oxidative coupling of rutin with 3-methylbenzthiazolinone-2-hydrazone using acidic ceric ammonium sulfate as the oxidizing agent. The solution is made alkaline with a buffer and the absorbance measured at 430 nm against a reagent blank. The method is precise and accurate. The applicability of the method was tested by analyzing the pure drug and commercial formulations of rutin. © 1990.

引用

页码：126 / 131

页数：6

共 29 条

[1] BANDYUKOVA VA, 1960, APTECHN DELO, V6, P24
[2] OPTIMIZATION OF OVERPRESSURED LAYER CHROMATOGRAPHY OF POLAR, NATURALLY-OCCURRING COMPOUNDS BY THE PRISMA MODEL
DALLENBACHTOELKE, K
NYIREDY, S
MEIER, B
STICHER, O
[J]. JOURNAL OF CHROMATOGRAPHY, 1986, 365 : 63 - 72
[3] DAVIDEK J, 1957, CESK FARM, V6, P449
[4] ELKOMMOS ME, 1982, J PHARM BELG, V37, P150
[5] ELKOMMOS ME, 1978, FARM ZH-KIEV, V3, P60
[6] ELKOMMOS ME, 1982, ARCH PHARM CHEMI SCI, V10, P146
[7] AUTOMATED COLORIMETRIC MICRODETERMINATION OF PHENOLS BY OXIDATIVE COUPLING WITH 3-METHYL-2-BENZOTHIAZOLINONE HYDRAZONE
FRIESTAD, HO
OTT, DE
GUNTHER, FA
[J]. ANALYTICAL CHEMISTRY, 1969, 41 (13) : 1750 - &
[8] GALENSA R, 1980, DTSCH APOTH ZTG, V120, P737
[9] GARG BS, 1971, INDIAN J APPL CHEM, V34, P17
[10] GASPARIC J, 1977, MIKROCHIM ACTA WEIN, V1, P231

← 1 2 3 →