STUDIES WITH STABLE ISOTOPES .1. CHANGES IN PHENYTOIN PHARMACOKINETICS AND BIOTRANSFORMATION DURING MONOTHERAPY

被引：23

作者：

BROWNE, TR

EVANS, JE

SZABO, GK

EVANS, BA

GREENBLATT, DJ

SCHUMACHER, GE

机构：

[1] TUFTS UNIV,SCH MED,EUNICE KENNEDY SHRIVER CTR,MASS SPECTROMETRY LAB,BOSTON,MA 02111

[2] BOSTON UNIV,SCH MED,DEPT NEUROL,BOSTON,MA 02118

[3] BOSTON UNIV,SCH MED,DEPT PHARMACOL,BOSTON,MA 02118

[4] NORTHEASTERN UNIV,COLL PHARM & ALLIED HLTH PROFESS,BOSTON,MA 02115

[5] TUFTS UNIV,SCH MED,DEPT PSYCHIAT,DIV CLIN PHARMACOL,BOSTON,MA 02111

[6] TUFTS UNIV,SCH MED,DEPT MED,BOSTON,MA 02111

[7] TUFTS UNIV,NEW ENGLAND MED CTR HOSP,MEDFORD,MA 02155

来源：

关键词：

D O I：

10.1002/j.1552-4604.1985.tb02799.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：43 / 50

页数：8

共 23 条

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[3] BROWN T, 1983, EPILEPSY, P175
[4] KINETIC EQUIVALENCE OF STABLE-ISOTOPE-LABELED AND UNLABELED PHENYTOIN
BROWNE, TR
VANLANGENHOVE, A
COSTELLO, CE
BIEMANN, K
GREENBLATT, DJ
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (04) : 511 - 515
[5] BROWNE TR, 1983, SYNTHESIS APPLICATIO, P343
[6] CHANG T, 1982, ANTIEPILEPTIC DRUGS, P209
[7] NON-LINEAR KINETICS OF PHENYTOIN IN CHILDREN
DODSON, WE
[J]. NEUROLOGY, 1982, 32 (01) : 42 - 48
[8] EVANS JE, DETERMINATION STABLE
[9] GIBALDI M, 1975, PHARMACOKINETICS
[10] Glantz S., 1981, PRIMER BIOSTATISTICS