A ROUTE TO GLYCALS IN THE ALLAL AND GULAL SERIES - SYNTHESIS OF THE THIOSUGAR OF ESPERAMICIN-A1

被引：57

作者：

WITTMAN, MD

HALCOMB, RL

DANISHEFSKY, SJ

GOLIK, J

VYAS, D

机构：

[1] YALE UNIV,DEPT CHEM,NEW HAVEN,CT 06511

[2] BRISTOL MYERS SQUIBB CO,WALLINGFORD,CT 06492

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 07期

关键词：

D O I：

10.1021/jo00294a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Axial anomeric sulfoxides generated via thio-phenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the method led to the synthesis of the esperamicin thiosugar, thereby establishing its absolute configuration. © 1990, American Chemical Society. All rights reserved.

引用

页码：1979 / 1981

页数：3

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