RADICAL CYCLIZATIONS OF N-VINYLIC ALPHA-CHLOROACETAMIDES - 5-ENDO-TRIG AND 4-EXO-TRIG CYCLIZATIONS

被引：98

作者：

ISHIBASHI, H

NAKAMURA, N

SATO, T

TAKEUCHI, M

IKEDA, M

机构：

[1] Kyoto Pharmaceutical University, Kyoto, 607, Misasagi, Yamashina

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 14期

关键词：

D O I：

10.1016/S0040-4039(00)74314-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bu3SnH mediated radical cyclizations of N-vinylic alpha-chloroacetamides proceeded in a "disfavored" 5-endo-trig manner to give five-membered lactams. Some exceptions where the 4-exo cyclization predominates are also described.

引用

页码：1725 / 1728

页数：4

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