STEREOCONTROLLED SYNTHESES OF DIEQUATORIAL AND AXIAL EQUATORIAL FUROFURAN LIGNANS

被引：32

作者：

OGIKU, T ^{[1
]}

YOSHIDA, SI ^{[1
]}

OHMIZU, H ^{[1
]}

IWASAKI, T ^{[1
]}

机构：

[1] TANABE SEIYAKU CO LTD,APPL BIOCHEM RES LAB,OSAKA 532,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1995年 / 60卷 / 05期

关键词：

D O I：

10.1021/jo00110a016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl piperitol, a representative example of the diequatorial furofuran lignan, was synthesized in a good overall yield based on a highly stereocontrolled conjugate addition-aldol reaction. Fargesin, a representative example of the axial-equatorial furofuran lignans, was also synthesized in a good overall yield based on a new method for inversion of the stereochemistry at C-4 of 5a.

引用

页码：1148 / 1153

页数：6

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