ASYMMETRIC REDUCTIONS WITH FREELY AND NON-FREELY ROTATING AMIDE GROUP NADH MODELS

被引：22

作者：

COMBRET, Y ^{[1
]}

TORCHE, JJ ^{[1
]}

BINAY, P ^{[1
]}

DUPAS, G ^{[1
]}

BOURGUIGNON, J ^{[1
]}

QUEGUINER, G ^{[1
]}

机构：

[1] INST NATL SUPER APPL, IRCOF, URA 1429, BP 08, F-76131 MONT ST AIGNAN, FRANCE

来源：

CHEMISTRY LETTERS | 1991年 / 01期

关键词：

D O I：

10.1246/cl.1991.125

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

NADH models with a freely or non freely rotating chiral amide group have been synthesized and used in the reduction of methyl benzoylformate. The same major enantiomer was obtained in all cases. A blocked reagent bearing a phenylalaninol group as chiral auxiliary allows one to obtain a high e.e.

引用

页码：125 / 128

页数：4

共 11 条

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