BORON-CONTAINING NUCLEIC-ACIDS .3. 5'-P-BORANE-SUBSTITUTED THYMIDINE MONOPHOSPHATE AND TRIPHOSPHATE

被引：72

作者：

TOMASZ, J ^{[1
]}

SHAW, BR ^{[1
]}

PORTER, K ^{[1
]}

SPIELVOGEL, BF ^{[1
]}

SOOD, A ^{[1
]}

机构：

[1] BORON BIOL,RALEIGH,NC 27606

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1992年 / 31卷 / 10期

关键词：

D O I：

10.1002/anie.199213731

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The attachment of the BH3 group to the phosphorus atom is the crucial step in the synthesis of boranophosphate 1 and -triphosphate 2. These compounds could be as useful in biochemical and molecular biological investigations as the related thiophosphates because of the prochiral (in 1) and chiral (in 2) phosphorus centers and the similar charge distribution to the thiophosphates. [GRAPHICS]

引用

页码：1373 / 1375

页数：3

共 34 条

[31] P-1-(THYMIDINE 5'-)P-1-AMINO-TRIPHOSPHATE - SYNTHESIS, HYDROLYSIS AND REACTION WITH CYTIDINE IN ALKALI [J].