HIGH-RATE OF RIFAMPICIN RESISTANCE OF MYCOBACTERIUM-TUBERCULOSIS IN THE TAIF REGION OF SAUDI-ARABIA

被引:34
作者
JARALLAH, JS [1 ]
ELIAS, AK [1 ]
ALHAJJAJ, MS [1 ]
BUKHARI, MS [1 ]
ALSHAREEF, AHM [1 ]
ALSHAMMARI, SA [1 ]
机构
[1] CHEST DIS HOSP,TAIF,SAUDI ARABIA
来源
TUBERCLE AND LUNG DISEASE | 1992年 / 73卷 / 02期
关键词
D O I
10.1016/0962-8479(92)90065-R
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
This retrospective study was undertaken to determine the prevalence and pattern of resistance to antituberculosis drugs among patients with sputum-proven pulmonary tuberculosis who were seen in Taif Chest Hospital over 24 months (between June 1986 and May 1988). The overall prevalence was 22.6% and the majority (53%) were resistant to two drugs. Resistance to streptomycin was most frequent (16%) followed by rifampicin (15%). Resistance to isoniazid was surprisingly low (6.5%). 23.3% of the resistant group had previously received antituberculosis drugs as against 15.4% in the sensitive group. There was a significant association between previous therapy and resistance to antituberculosis drugs. Recommendations to reduce the problem of resistance and to improve compliance are discussed.
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收藏
页码:113 / 115
页数:3
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