AMINO-ACID SEQUENCE OF 3 NON-CURAREMIMETIC TOXINS FROM NAJA-NIVEA VENOM

被引：32

作者：

BOTES, DP ^{[1
]}

VILJOEN, CC ^{[1
]}

机构：

[1] CSIR, NATL CHEM RES LAB, PRETORIA, SOUTH AFRICA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1976年 / 446卷 / 01期

关键词：

D O I：

10.1016/0005-2795(76)90091-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three toxins of the non-curarimimetic type were isolated from the venom of the Cape cobra N. nivea. The basic and hydrophobic amino acids are dominant in all 3 toxins. They comprise 60 amino acid residues with 4 intrachain disulfide linkages. The toxins are characterized with respect to their linear structures and immunochemical properties. Toxicity and hemolytic data [mice, guinea pigs] suggest a much higher affinity for receptors on the heart cell membrane than for that of the red cell.

引用

页码：1 / 9

页数：9

共 41 条

[1] DIRECT LYTIC FACTOR OF COBRA VENOM - PURIFICATION AND CHEMICAL CHARACTERIZATION [J].