EPIDEMIOLOGY OF DIABETES-MELLITUS IN THE ELDERLY IN NORTHERN GREECE - A POPULATION STUDY

被引：19

作者：

PAPAZOGLOU, N ^{[1
]}

MANES, C ^{[1
]}

CHATZIMITROFANOUS, P ^{[1
]}

PAPADELI, E ^{[1
]}

TZOUNAS, K ^{[1
]}

SCARAGAS, G ^{[1
]}

KONTOGIANNIS, I ^{[1
]}

ALEXIADES, D ^{[1
]}

机构：

[1] ST PAUL GEN HOSP,DEPT INTERNAL MED,THESSALONIKI,GREECE

来源：

DIABETIC MEDICINE | 1995年 / 12卷 / 05期

关键词：

EPIDEMIOLOGY; TYPE; 2; DIABETES; GREECE; DIABETES IN THE ELDERLY; IMPAIRED GLUCOSE TOLERANCE;

D O I：

10.1111/j.1464-5491.1995.tb00502.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This population based study was undertaken to ascertain the overall prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in the elderly using the WHO criteria. The role of obesity in the development of DM or IGT has been investigated for both sexes per decade of age. Furthermore the potential for DM to increase with age, as has been suggested before, has been evaluated using the IGT as a proportion of total glucose intolerance (IGT/TGI) for the same parts of the tested sample. From the 647 persons registered as elderly people in a small town in northern Greece (total population 5875 people), 66 persons did not participate in this survey. Fifty-six subjects (9.7 %) had previously diagnosed DM. The remainder were tested using fasting blood glucose measurements or an oral glucose tolerance test (OGTT). The prevalence of previously undiagnosed DM according to fasting blood glucose values or after 2 h of 75 g load values was 10.1 % and 9.3 %, respectively. Thus the overall prevalence of DM was 29.1 % and of IGT was 15.1 %. These data support an increased frequency of DM (65 % previously undiagnosed) and IGT in the elderly, whereas this population's susceptibility seems to decline in the older groups for both sexes. Obesity remains a risk factor for DM and IGT particularly among the younger groups although its role has been found to decline with age.

引用

页码：397 / 400

页数：4

共 18 条

[1] Knowler WC, Bennet PH, Hamman RF, Miller M., Diabetes incidence and prevalence in Pima Indians: a 19 fold greater incidence than in Rochester Minnesota, Am J Epidemiol, 108, pp. 497-505, (1978)
[2] Bennet PH., Diabetes in the elderly: diagnosis and epidemiology, Geriatrics, 39, pp. 37-41, (1984)
[3] Zimmet P., King H., Taylor R., Raper LR, Balkau B., Borger J., Et al., The high prevalence of diabetes mellitus, impaired glucose tolerance and diabetic retinopathy in Nauru—the 1982 Survey, Diabetes Res, 1, pp. 13-18, (1984)
[4] Tuomilento J., Nissinen A., Kivela L., Pekanen J., Kaarsalo E., Wolf E., Et al., Prevalence of diabetes mellitus in elderly men aged 65 to 84 years in eastern and western Finland, Diabetologia, 29, pp. 611-615, (1986)
[5] Abbot RD, Donnahue RP, MacMahan SW., Diabetes and the risk of stroke. The Honolulu Heart Program, J Am Med Assoc, 7, pp. 949-955, (1987)
[6] Katsilambros N., Aliferis K., Darviri, Tsapogas P., Alexiou Z., Tritos N., Et al., Evidence for an increase in the prevalence of known Diabetes in a sample of an urban population in Greece, Diabetic Med, 10, pp. 87-90, (1993)
[7] Diabetes Mellitus, (1985)
[8] Mykkanen L., Laakso M., Uusitupa M., Pyorala K., Prevalence of diabetes and impaired glucose tolerance in elderly subjects and their association with obesity and family history of diabetes, Diabetes Care, 13, pp. 1099-1105, (1990)
[9] Dowse KG, Zimmet ZP., The prevalence and incidence of non‐insulin‐dependent diabetes mellitus, Frontiers of Diabetes Research: Current Trends in Non‐insulin‐dependent Diabetes Mellitus, pp. 37-59, (1989)
[10] Horton E., Jeanrenaud B., Obesity and diabetes mellitus, Ellenberg and Rifkin's Diabetes Mellitus: Theory and Practice, pp. 457-463, (1990)

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