STEREOCONTROLLED ADDITION OF 2-LITHIOTHIAZOLE TO THE NITRONE DERIVED FROM D-GLYCERALDEHYDE ACETONIDE - A REVISION AND EXTENSION

被引：49

作者：

DONDONI, A ^{[1
]}

FRANCO, S ^{[1
]}

MERCHAN, FL ^{[1
]}

MERINO, P ^{[1
]}

TEJERO, T ^{[1
]}

机构：

[1] UNIV ZARAGOZA,CSIC,ICMA,DEPT QUIM ORGAN,ZARAGOZA,SPAIN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 34期

关键词：

THIAZOLE; NITRONES; HYDROXYLAMINES; AMINOHOMOLOGATION; STEREOCONTROLLED ADDITION;

D O I：

10.1016/S0040-4039(00)73938-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The sense of diastereoselective addition of 2-lithiothiazole 1a to the nitrone 2 derived from D-glyceraldehyde is reversed by the use of Lewis acids (Et2AlCl, TiCl4) as complexing agents; the configuration of the hydroxylamine adduct obtained from 1a and 2 in the absence of the above chelating agents, previously reported from these laboratories was revised.

引用

页码：5475 / 5478

页数：4

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