ETHYL PHENYLSULFINYL FLUOROACETATE, A NEW AND VERSATILE REAGENT FOR THE PREPARATION OF ALPHA-FLUORO-ALPHA,BETA-UNSATURATED CARBOXYLIC-ACID ESTERS

被引：61

作者：

ALLMENDINGER, T

机构：

[1] Central Research Laboratories, Ciba-Geigy AG

来源：

TETRAHEDRON | 1991年 / 47卷 / 27期

关键词：

D O I：

10.1016/S0040-4020(01)80956-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound 2 can be alkylated with a wide range of alkyl halides and Michael acceptors. Subsequent thermal elimination of phenyl sulfinic acid 3 leads to alpha-fluoro-alpha,beta-unsaturated ethyl carboxylates 5 and 10, an important class of intermediates for fluorine containing biologically active compounds.

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页码：4905 / 4914

页数：10

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