SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .8. SYNTHESIS OF DISUBSTITUTED 2-SUBSTRATE CONDENSATION PRODUCTS AS INHIBITORS OF RAT ADENYLATE KINASES

被引：14

作者：

KAPPLER, F ^{[1
]}

HAI, TT ^{[1
]}

ABO, M ^{[1
]}

HAMPTON, A ^{[1
]}

机构：

[1] FOX CHASE CANC CTR,INST CANC RES,PHILADELPHIA,PA 19111

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 10期

关键词：

D O I：

10.1021/jm00352a016

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1179 / 1184

页数：6

共 22 条

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[8] DESIGN OF SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .3. SPECIES AND ISOZYMIC DIFFERENCES BETWEEN MAMMALIAN AND BACTERIAL ADENYLATE KINASES IN SUBSTITUENT TOLERANCE IN AN ENZYME-SUBSTRATE COMPLEX [J].

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[9] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .6. SYNTHESIS AND EVALUATION OF 2-SUBSTRATE CONDENSATION PRODUCTS AS INHIBITORS OF HEXOKINASES AND THYMIDINE KINASES [J].

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[10] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .5. DIFFERENTIAL-EFFECTS OF THYMIDINE SUBSTITUENTS ON AFFINITY FOR RAT THYMIDINE KINASE ISOZYMES [J].

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JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (06) :644-649

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