Transmission of multidrug-resistant and extensively drug-resistant tuberculosis in rural Bangladesh: lessons learnt

被引：2

作者：

Gumusboga, A. ^{[1
]}

Aung, K. J. M. ^{[2
]}

Rigouts, L. ^{[1
]}

Van Deun, A. ^{[1
,3
]}

机构：

[1] Inst Trop Med, Mycobacteriol Unit, Nationalestr 155, B-2000 Antwerp, Belgium

[2] Damien Fdn Bangladesh, Dhaka, Bangladesh

[3] Int Union TB & Lung Dis, Paris, France

来源：

PUBLIC HEALTH ACTION | 2012年 / 2卷 / 03期

关键词：

tuberculosis; transmission; MDR-TB; XDR-TB; Bangladesh;

D O I：

10.5588/pha.12.0015

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

We report community transmission of multidrug-resistant (MDR-) and extensively drug-resistant tuberculosis (XDRTB) documented by fingerprinting, with secondary cases appearing over a period of 10 years. The index case failed MDR-TB treatment, with amplification to XDR-TB after refusing treatment when first diagnosed and developing pre-XDR-TB on private treatment. Some of the first MDRTB patients were not started on appropriate treatment due to delayed diagnosis or to excessively rigid application of National TB Programme guidelines. Early presumptive MDR-and XDR-TB diagnosis and removal of barriers, such as obligatory hospitalisation, could have stopped this trend of resistance amplification and transmission.

引用

页码：76 / 78

页数：3

共 10 条

[1]

Low HIV infection rates among tuberculosis patients in Dhaka, Bangladesh [J].

Alam, MS ;

Sarker, MS ;

Mahmud, AM ;

Faruq, AKM ;

Begum, J ;

de Colombani, P ;

Yirrell, D ;

Sack, DA ;

Azim, T .

INTERNATIONAL JOURNAL OF STD & AIDS, 2005, 16 (01) :86-88

[2]

BRANDER E, 1972, Tubercle, V53, P128, DOI 10.1016/0041-3879(72)90029-3

[3]

Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology [J].

Kamerbeek, J ;

Schouls, L ;

Kolk, A ;

vanAgterveld, M ;

vanSoolingen, D ;

Kuijper, S ;

Bunschoten, A ;

Molhuizen, H ;

Shaw, R ;

Goyal, M ;

vanEmbden, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (04) :907-914

[4]

Nardell E, 2010, INT J TUBERC LUNG D, V14, P1233

[5]

Newly developed primers for comprehensive amplification of the rpoB gene and detection of rifampin resistance in Mycobacterium tuberculosis [J].

Rigouts, Leen ;

Nolasco, Oscar ;

de Rijk, Pim ;

Nduwamahoro, Elie ;

Van Deun, Armand ;

Ramsay, Andy ;

Arevalo, Jorge ;

Portaels, Francoise .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (01) :252-254

[6]

Salim AH, 2006, INT J TUBERC LUNG D, V10, P1248

[7]

Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis [J].

Supply, Philip ;

Allix, Caroline ;

Lesjean, Sarah ;

Cardoso-Oelemann, Mara ;

Ruesch-Gerdes, Sabine ;

Willery, Eve ;

Savine, Evgueni ;

de Haas, Petra ;

van Deutekom, Henk ;

Roring, Solvig ;

Bifani, Pablo ;

Kurepina, Natalia ;

Kreiswirth, Barry ;

Sola, Christophe ;

Rastogi, Nalin ;

Vatin, Vincent ;

Gutierrez, Maria Cristina ;

Fauville, Maryse ;

Niemann, Stefan ;

Skuce, Robin ;

Kremer, Kristin ;

Locht, Camille ;

van Soolingen, Dick .

JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (12) :4498-4510

[8]

Van Deun A, 2004, INT J TUBERC LUNG D, V8, P23

[9]

Van Deun A, 2001, INT J TUBERC LUNG D, V5, P329

[10]

Short, Highly Effective, and Inexpensive Standardized Treatment of Multidrug-resistant Tuberculosis [J].

Van Deun, Armand ;

Maug, Aung Kya Jai ;

Salim, Md Abdul Hamid ;

Das, Pankaj Kumar ;

Sarker, Mihir Ranjan ;

Daru, Paul ;

Rieder, Hans L. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 182 (05) :684-692

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