BACTERIAL DEFENSES AGAINST OXIDATIVE STRESS

被引:297
作者
STORZ, G
TARTAGLIA, LA
FARR, SB
AMES, BN
机构
[1] GENENTECH INC, SAN FRANCISCO, CA 94080 USA
[2] HARVARD UNIV, SCH PUBL HLTH, TOXICOL LAB, BOSTON, MA 02115 USA
[3] UNIV CALIF BERKELEY, DIV BIOCHEM & MOLEC BIOL, BERKELEY, CA 94720 USA
关键词
D O I
10.1016/0168-9525(90)90278-E
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Bacteria treated with low doses of oxidants such as hydrogen peroxide adapt to subsequent high doses of these oxidants by inducing the expression of numerous genes. The study of these genes and the roles they play in defending bacteria against oxidative damage has given general insights into what oxidants are hazardous to cells, what cell constituents are damaged by oxidants, and how cells sense and respond to oxidative stress. © 1990.
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页码:363 / 368
页数:6
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