ESTIMATION OF THE LOWER LIMIT OF QUANTITATION, A METHOD DETECTION PERFORMANCE PARAMETER FOR BIOMEDICAL ASSAYS, FROM CALIBRATION CURVES

被引：13

作者：

KUCHARCZYK, N

机构：

[1] Wallace Laboratories, Division of Carter-Wallace, Inc., Cranbury

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1993年 / 612卷 / 01期

关键词：

D O I：

10.1016/0378-4347(93)80369-F

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A model for the lower limit of quantitation for biomedical chromatographic assays is proposed. It is based on the IUPAC definition for the limit of detection and can be estimated from assay calibration data. It has been applied to ten different sets of calibration data from various assays of drugs in biological matrices.

引用

页码：71 / 76

页数：6

共 16 条

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[2]

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[3]

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[4]

DRAPER NR, 1981, APPLIED REGRESSION A