ABORTION BEFORE 1ST LIVEBIRTH AND RISK OF BREAST-CANCER

被引:62
作者
HADJIMICHAEL, OC
BOYLE, CA
MEIGS, JW
机构
[1] YALE UNIV, SCH MED, CONNECTICUT CANC EPIDEMIOL UNIT, NEW HAVEN, CT 06510 USA
[2] YALE UNIV, SCH MED, DEPT EPIDEMIOL & PUBL HLTH, NEW HAVEN, CT 06510 USA
关键词
D O I
10.1038/bjc.1986.46
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The present study examined the association between abortion prior to a first livebirth and breast cancer risk among a cohort of 3,315 women who had been delivered of liveborn children between 1946 and 1965 in a group of private gynaecology practices in Connecticut [USA] and followed through 1980 for the incidence of cancer. Among women with one livebirth at the time of cohort identification, a spontaneous abortion before this livebirth was associated with a 3.5-fold increase in the risk of breast cancer. The elevation in risk was independent of some of the major risk factors of breast cancer and became more pronounced as the number of years since the abortion increased.
引用
收藏
页码:281 / 284
页数:4
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