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CHLAMYDIA-TRACHOMATIS PNEUMONIA INDUCES INVIVO PRODUCTION OF INTERLEUKIN-1 AND INTERLEUKIN-6

被引：38
作者：
MAGEE, DM
SMITH, JG
BLEICKER, CA
CARTER, CJ
BONEWALD, LF
SCHACHTER, J
WILLIAMS, DM
机构：
[1] UNIV TEXAS,HLTH SCI CTR,DEPT MED,SAN ANTONIO,TX 78284
[2] UNIV TEXAS,HLTH SCI CTR,DEPT MICROBIOL,SAN ANTONIO,TX 78284
[3] AUDIE L MURPHY MEM VET ADM MED CTR,DIV INFECT DIS,SAN ANTONIO,TX 78284
[4] UNIV CALIF SAN FRANCISCO,DEPT LAB MED,SAN FRANCISCO,CA 94143
来源：
INFECTION AND IMMUNITY | 1992年 / 60卷 / 03期
关键词：
D O I：
10.1128/IAI.60.3.1217-1220.1992
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1-alpha, IL-1-beta, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.
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页码：1217 / 1220
页数：4
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