BIOTRANSFORMATION OF GERMACRANE EPOXIDES BY CICHORIUM-INTYBUS

被引：40

作者：

PIET, DP ^{[1
]}

SCHRIJVERS, R ^{[1
]}

FRANSSEN, MCR ^{[1
]}

DEGROOT, A ^{[1
]}

机构：

[1] AGR UNIV WAGENINGEN,DEPT ORGAN CHEM,6703 HB WAGENINGEN,NETHERLANDS

来源：

TETRAHEDRON | 1995年 / 51卷 / 22期

关键词：

D O I：

10.1016/0040-4020(95)00272-A

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The biotransformation of germacrone-4,5-epoxide (2), germacrone-1,10-epoxide (3), isogermacrone-4,5-epoxide (5), germacrene B-4,5-epoxide (6) and germacrene B-I,10-epoxide (7) by a suspension of fresh chicory root (Cichorium intybus) was investigated. Enzyme catalysed cyclisations towards substituted guaianes and eudesmanes were observed.

引用

页码：6303 / 6314

页数：12

共 33 条

[1] BIOTRANSFORMATION OF GERMACRANE-TYPE SESQUITERPENOIDS BY ASPERGILLUS-NIGER [J].

ASAKAWA, Y ;

TAKAHASHI, H ;

TOYOTA, M .

PHYTOCHEMISTRY, 1991, 30 (12) :3993-3997

[2] MEDIUM-RING 1,5-DIENES .3. CYCLIZATION OF GERMACRA-1(10),4,7-(11)-TRIENE OXIDES [J].

BROWN, ED ;

SUTHERLAND, JK ;

SAM, TW .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1975, (22) :2332-2336

[3]

BUNTEL CJ, 1994, ACS SYM SER, V562, P52

[4] HPLC ISOLATION OF THE SESQUITERPENE HYDROCARBON GERMACRENE-B FROM LIME PEEL OIL AND ITS CHARACTERIZATION AS AN IMPORTANT FLAVOR IMPACT CONSTITUENT [J].

CLARK, BC ;

CHAMBLEE, TS ;

IACOBUCCI, GA .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1987, 35 (04) :514-518

[5] BIOMIMETIC CYCLIZATION OF 4-BETA, 5-ALPHA-EPOXY-6-BETA-ACETOXY-TRANS-GERMACR-1(10)-ENE TO FORM CIS-(1-BETA-H-5-BETA-H)-GUAIANES [J].

GARCIAGRANADOS, A ;

MOLINA, A ;

CABRERA, E .

TETRAHEDRON, 1986, 42 (01) :81-87

[6]

HIKINO H, 1977, CHEM PHARM BULL, V25, P6

[7] CONVENIENT METHOD FOR THE PREPARATION OF REACTIVE OXIRANES BY DIRECT EPOXIDATION [J].

IMUTA, M ;

ZIFFER, H .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (08) :1351-1352

[8]

Johnson W. S., 1991, TETRAHEDRON, V47, pxi

[9]

KUROYANAGI M, 1987, CHEM PHARM BULL, V35, P53

[10]

KUROYANAGI M, 1990, CHEM PHARM BULL, V38, P55, DOI 10.1248/cpb.38.55

← 1 2 3 4 →