THE P53-MDM2 AUTOREGULATORY FEEDBACK LOOP - A PARADIGM FOR THE REGULATION OF GROWTH-CONTROL BY P53

被引：184

作者：

PICKSLEY, SM ^{[1
]}

LANE, DP ^{[1
]}

机构：

[1] UNIV DUNDEE,DEPT BIOCHEM,CRC,CELL TRANSFORMAT LAB,DUNDEE DD1 4HN,SCOTLAND

来源：

BIOESSAYS | 1993年 / 15卷 / 10期

关键词：

D O I：

10.1002/bies.950151008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：689 / 690

页数：2

共 22 条

[1] MDM2 EXPRESSION IS INDUCED BY WILD TYPE-P53 ACTIVITY [J].

BARAK, Y ;

JUVEN, T ;

HAFFNER, R ;

OREN, M .

EMBO JOURNAL, 1993, 12 (02) :461-468

[2] ENHANCED BINDING OF A 95-KDA PROTEIN TO P53 IN CELLS UNDERGOING P53-MEDIATED GROWTH ARREST [J].

BARAK, Y ;

OREN, M .

EMBO JOURNAL, 1992, 11 (06) :2115-2121

[3]

BASERGA R, 1991, J CELL SCI, V98, P433

[4] MOLECULAR ANALYSIS AND CHROMOSOMAL MAPPING OF AMPLIFIED GENES ISOLATED FROM A TRANSFORMED MOUSE 3T3-CELL LINE [J].

CAHILLYSNYDER, L ;

YANGFENG, T ;

FRANCKE, U ;

GEORGE, DL .

SOMATIC CELL AND MOLECULAR GENETICS, 1987, 13 (03) :235-244

[5] THE TUMOR-SUPPRESSOR P53 REGULATES ITS OWN TRANSCRIPTION [J].

DEFFIE, A ;

WU, HY ;

REINKE, V ;

LOZANO, G .

MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (06) :3415-3423

[6] TUMORIGENIC POTENTIAL ASSOCIATED WITH ENHANCED EXPRESSION OF A GENE THAT IS AMPLIFIED IN A MOUSE-TUMOR CELL-LINE [J].

FAKHARZADEH, SS ;

TRUSKO, SP ;

GEORGE, DL .

EMBO JOURNAL, 1991, 10 (06) :1565-1569

[7] WILD-TYPE P53 ACTIVATES TRANSCRIPTION INVITRO [J].

FARMER, G ;

BARGONETTI, J ;

ZHU, H ;

FRIEDMAN, P ;

PRYWES, R ;

PRIVES, C .

NATURE, 1992, 358 (6381) :83-86

[8] THE MDM-2 ONCOGENE CAN OVERCOME WILD-TYPE P53 SUPPRESSION OF TRANSFORMED-CELL GROWTH [J].

FINLAY, CA .

MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (01) :301-306

[9] A TRANSCRIPTIONALLY ACTIVE DNA-BINDING SITE FOR HUMAN P53 PROTEIN COMPLEXES [J].

FUNK, WD ;

PAK, DT ;

KARAS, RH ;

WRIGHT, WE ;

SHAY, JW .

MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (06) :2866-2871

[10] ONCOGENIC FORMS OF P53 INHIBIT P53-REGULATED GENE-EXPRESSION [J].

KERN, SE ;

PIETENPOL, JA ;

THIAGALINGAM, S ;

SEYMOUR, A ;

KINZLER, KW ;

VOGELSTEIN, B .

SCIENCE, 1992, 256 (5058) :827-830

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