INVESTIGATION OF STRUCTURE AND DYNAMICS IN MEMBRANE-PROTEINS USING SITE-DIRECTED SPIN-LABELING

被引：363

作者：

HUBBELL, WL

ALTENBACH, C

机构：

[1] WL Hubbell and C Altenbach, Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, CA 90024-7008

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(94)90219-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Site-directed spin labeling has emerged as a powerful method for determining the structure and topography of proteins. The technique has recently been extended to include time-resolved detection of structural changes with high spatial resolution. The current state of the art and future directions are reviewed.

引用

页码：566 / 573

页数：8

共 26 条

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