SYNTHESIS OF NONNATURAL BRANCHED POLYSACCHARIDES - REGIOSELECTIVE INTRODUCTION OF ALPHA-MANNOSIDE BRANCHES INTO CHITIN

被引：17

作者：

KURITA, K ^{[1
]}

KOBAYASHI, M ^{[1
]}

MUNAKATA, T ^{[1
]}

ISHII, S ^{[1
]}

NISHIMURA, SI ^{[1
]}

机构：

[1] HOKKAIDO UNIV, GRAD SCH SCI, DIV BIOL SCI, SAPPORO, HOKKAIDO 060, JAPAN

来源：

CHEMISTRY LETTERS | 1994年 / 11期

关键词：

D O I：

10.1246/cl.1994.2063

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Phthaloyl-chitosan was converted into 3-O-acetyl-6-O-trimethylsilyl-N-phthaloyl-chitosan, which was then subjected to the glycosylation of a peracetylated mannose orthoester to form an alpha-(1-->6) linkage. Subsequent deprotection followed by N-acetylation afforded chitins having mannose branches. The branched chitins were readily soluble in water and showed strong affinity for concanavalin A.

引用

页码：2063 / 2066

页数：4

共 13 条

[1]

CHIHARA G, 1982, INT J TISSUE REACT, V4, P207

[2]

CHIHARA G, 1969, Nature (London), V222, P687

[3] FORMATION OF BRANCHED-CHAIN, SOLUBLE POLYSACCHARIDES FROM CHITOSAN [J].

HALL, LD ;

YALPANI, M .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1980, (23) :1153-1154

[4] TAILORED-RHEOLOGY - CHITOSAN DERIVATIVES WITH BRANCHED PENDANT SUGAR CHAINS [J].

HALL, LD ;

HOLME, KR .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (03) :217-218

[5] NOVEL REACTION ROUTE INCLUDING ENZYMATIC-REACTION FOR A SYNTHESIS OF A BRANCHED POLYSACCHARIDE [J].

HATANAKA, K ;

SONG, SC ;

MARUYAMA, A ;

AKAIKE, T ;

KOBAYASHI, A ;

KUZUHARA, H .

JOURNAL OF CARBOHYDRATE CHEMISTRY, 1992, 11 (08) :1027-1037

[6] CHITOSAN DERIVATIVES BEARING C-10-ALKYL GLYCOSIDE BRANCHES - A TEMPERATURE-INDUCED GELLING POLYSACCHARIDE [J].

HOLME, KR ;

HALL, LD .

MACROMOLECULES, 1991, 24 (13) :3828-3833

[7]

KURITA K, 1977, MAKROMOL CHEM, V178, P3197

[8]

KUZUHARA H, 1988, 14TH INT CARB S STOC, P201

[9] ANTI-TUMOR EFFECT OF SCHIZOPHYLLAN, AN IMMUNOMODULATOR, ON SYNGENEIC TUMORS [J].

MITANI, M ;

ARIGA, T ;

MATSUO, T ;

ASANO, T ;

SAITO, G .

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1980, 2 (03) :174-175

[10] AN EFFICIENT METHOD FOR THE SYNTHESES OF NOVEL AMPHIPHILIC POLYSACCHARIDES BY REGIOSELECTIVE AND THERMOSELECTIVE MODIFICATIONS OF CHITOSAN [J].

NISHIMURA, SI ;

MIURA, Y ;

REN, LD ;

SATO, M ;

YAMAGISHI, A ;

NISHI, N ;

TOKURA, S ;

KURITA, K ;

ISHII, S .

CHEMISTRY LETTERS, 1993, (09) :1623-1626

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