UTILIZATION OF FINE-NEEDLE ASPIRATION BIOPSY IN THE DIAGNOSIS OF METASTATIC TUMORS TO THE PANCREAS

被引:26
作者
CARSON, HJ [1 ]
GREEN, LK [1 ]
CASTELLI, MJ [1 ]
REYES, CV [1 ]
PRINZ, RA [1 ]
GATTUSO, P [1 ]
机构
[1] LOYOLA UNIV,MED CTR,DEPT PATHOL,MAYWOOD,IL 60153
关键词
PANCREAS; METASTASIS; FINE-NEEDLE ASPIRATION BIOPSY;
D O I
10.1002/dc.2840120104
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
There is relatively little information concerning the use of fine-needle aspiration biopsy (FNAB) to diagnose a mass in the pancreas that is secondary to metastatic tumor. This study reviews the incidence and types of neoplasms which metastasize to the pacreas and assesses the contribution FNAB can make in their diagnosis. Of 117 radiologically guided FNABs of the pancreas, 11% (n = 13) showed metastatic malignancy. Nine patients had a previous history of malignancy while four patients presented with a pancreatic mass and were subsequently found to have widespread malignant disease. The majority of metastatic lesions were epithelial (77%, n = 10). Patients outcomes were generally poor (mean survival 2.8 mo). Metastases to the pancreas occur from a variety of primary sites and should be considered in patients with a pancreatic mass and a history of prior malignancy. FNAB is useful in diagnosing these metastases and this is clinically important because of their poor prognosis.
引用
收藏
页码:8 / 13
页数:6
相关论文
共 23 条
[1]  
Tao L-C, Ho C-S, McLoughlin MJ, McHattie J, Percutaneous fine needle aspiration biopsy of the pancreas: cytodiagnosis of pancreatic carcinoma, Acta Cytol, 22, pp. 215-220, (1978)
[2]  
Mitchell ML, Carney CN, Cytologic criteria for the diagnosis of pancreatic carcinoma, Am J Clin Pathol, 83, pp. 171-176, (1985)
[3]  
Soreide O, Skaarland E, Pedersen OM, Larssen TB, Arnesjo B, Fine‐needle biopsy of the pancreas: results of 204 routinely performed biopsies in 190 patients, World Journal of Surgery, 9, pp. 960-965, (1985)
[4]  
Alpern GA, Dekker A, Fine needle aspiration cytology of the pancreas: an analysis of its use in 52 patients, Acta Cytol, 29, pp. 873-878, (1985)
[5]  
Frias-Hidvegi D, Guides to clinical aspiration biopsy: liver and pancreas, pp. 205-321, (1988)
[6]  
Mitchell ML, Bittner CA, Wills JS, Parker FP, Fine needle aspiration cytology of the pancreas: a retrospective study of 73 cases, Acta Cytol, 32, pp. 447-451, (1988)
[7]  
Soudah B, Fritsch RS, Wittekind C, Hilka B, Spindler B, Value of the cytologic analysis of fine needle aspiration biopsy specimens in the diagnosis of pancreatic carcinomas, Acta Cytol, 33, pp. 875-880, (1989)
[8]  
Cohen MB, Egerter DP, Holly EA, Ahn DK, Miller TR, Pancreatic adenocarcinoma: regression analysis to identify improved cytologic criteria, Diagn Cytopathol, 7, pp. 341-345, (1991)
[9]  
Benning TL, Silverman JF, Berns LA, Geisinger KR, Fine needle aspiration of metastatic and hematologic malignancies clinically mimicking pancreatic carcinoma, Acta Cytol, 36, pp. 471-476, (1992)
[10]  
Jennette JC, Wick MR, Immunocytochemical techniques for immunofluorescence, immunoenzyme, and immunoelectron microscopy, Immunohistology in diagnostic pathology, pp. 1-27, (1988)