MOLECULAR CYTOTAXONOMY OF PRIMATES BY CHROMOSOMAL INSITU SUPPRESSION HYBRIDIZATION

被引：166

作者：

WIENBERG, J

JAUCH, A

STANYON, R

CREMER, T

机构：

[1] UNIV HEIDELBERG,INST HUMANGENET & ANTHROPOL,NEUENHEIMER FELD 328,W-6900 HEIDELBERG,GERMANY

[2] UNIV MUNICH,INST ANTHROPOL & HUMANGENET,W-8000 MUNICH 2,GERMANY

[3] UNIV GENOA,IST ANTROPOL,I-16126 GENOA,ITALY

来源：

GENOMICS | 1990年 / 8卷 / 02期

关键词：

D O I：

10.1016/0888-7543(90)90292-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of catarrhines, platyrrhines, and prosimians. By this approach rearrangements of chromosomes that occurred during hominoid evolution are visualized directly at the level of DNA sequences, even in primate species with pronounced chromosomal shuffles. © 1990.

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页码：347 / 350

页数：4

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