A COMMON DENOMINATOR OF GROWTH CONE GUIDANCE AND COLLAPSE

被引:89
作者
WALTER, J
ALLSOPP, TE
BONHOEFFER, F
机构
[1] Max-Planck-Institutfür Entwicklungsbiologie, D-7400 Tübingen
关键词
D O I
10.1016/0166-2236(90)90097-T
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Axonal guidance in the retinotectal system and in spinal nerve segmentation is based on repulsion or inhibition. In both systems the membrane glycoprotein responsible for the guiding activity is capable of inducing growth cone collapse. We discuss two models of axonal guidance that correlate axonal guidance and growth cone collapse. The models are applicable to axon guidance by membrane-associated or diffusible stimuli, and are not based on preferential adhesion of axons to certain substrata. © 1990.
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页码:447 / 452
页数:6
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