MONITORING OF OXIDATIVE FREE-RADICAL DAMAGE INVIVO - ANALYTICAL ASPECTS

被引:110
作者
HAGEMAN, JJ [1 ]
BAST, A [1 ]
VERMEULEN, NPE [1 ]
机构
[1] FREE UNIV AMSTERDAM, DEPT PHARMACOCHEM, DE BOELELAAN 1083, 1081 HV AMSTERDAM, NETHERLANDS
关键词
BIO-MONITORING; FREE RADICAL DAMAGE; INVIVO; ANALYTICAL ASPECTS; OXIDATIVE STRESS;
D O I
10.1016/0009-2797(92)90001-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Free radical damage is an important factor in many pathological and toxicological processes. During the last decade a wide range of methods has been developed to determine free radical damage in various biological fluids and at various stages of development. This review offers an overview of the state of the art of monitoring free radical damage in vivo, with special emphasis on the analytical aspects of non-invasive methods.
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页码:243 / 293
页数:51
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