MULTIPLE RECEPTORS FOR ENDOTOXIN

被引：185

作者：

WRIGHT, SD

机构：

[1] Laboratory of Cellular Physiology and Immunology, The Rockefeller University, NY

来源：

CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 01期

关键词：

D O I：

10.1016/0952-7915(91)90082-C

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent studies have identified three classes of receptor molecules involved in recognition of endotoxin. Two classes of receptors, the CD18 antigens and the scavenger receptor, recognize lipopolysaccharide directly and function principally in its catabolism. A third molecule, CD14, recognizes lipopolysaccharide with the aid of a serum protein, lipopolysaccharide-binding protein, and may be a principal mediator of secretory responses of leukocytes.

引用

页码：83 / 90

页数：8

共 43 条

[1] OLIGOSPECIFICITY OF THE CELLULAR ADHESION RECEPTOR MAC-1 ENCOMPASSES AN INDUCIBLE RECOGNITION SPECIFICITY FOR FIBRINOGEN [J].