OCCURRENCE OF AN ACTIN-INSERTING DOMAIN IN TENSIN

被引：27

作者：

WEIGT, C

GAERTNER, A

WEGNER, A

KORTE, H

MEYER, HE

机构：

[1] Institute of Physiological Chemistry Ruhr-University Bochum

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1992年 / 227卷 / 02期

关键词：

INSERTIN; TENSIN; ACTIN; MEMBRANE ADHESION SITES; AMINO ACID SEQUENCE;

D O I：

10.1016/0022-2836(92)90915-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have previously described a protein called "insertin" that binds strongly to barbed ends of actin filaments and permits polymerization of actin filaments by insertion of actin monomers between the barbed ends and barbed end-bound insertin. We determined the amino acid sequence of insertin and found that the primary structure of insertin is almost identical to amino acid residues 862 to 1212 of the actin-binding protein tensin. © 1992.

引用

收藏

页码：593 / 595

页数：3

相关论文

共 9 条

[1] PRESENCE OF AN SH2 DOMAIN IN THE ACTIN-BINDING PROTEIN TENSIN [J].

DAVIS, S ;

LU, ML ;

LO, SH ;

LIN, S ;

BUTLER, JA ;

DRUKER, BJ ;

ROBERTS, TM ;

AN, Q ;

CHEN, LB .

SCIENCE, 1991, 252 (5006) :712-715

[2] MECHANISM OF THE INSERTION OF ACTIN MONOMERS BETWEEN THE BARBED ENDS OF ACTIN-FILAMENTS AND BARBED END-BOUND INSERTIN [J].

GAERTNER, A ;

WEGNER, A .

JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 1991, 12 (01) :27-36

[3] ELECTRON MICROSCOPE STUDIES ON STRUCTURE OF NATURAL AND SYNTHETIC PROTEIN FILAMENTS FROM STRIATED MUSCLE [J].

HUXLEY, HE .

JOURNAL OF MOLECULAR BIOLOGY, 1963, 7 (03) :281-&

[4] NUCLEATED POLYMERIZATION OF ACTIN FROM THE MEMBRANE-ASSOCIATED ENDS OF MICROVILLAR FILAMENTS IN THE INTESTINAL BRUSH-BORDER [J].

MOOSEKER, MS ;

POLLARD, TD ;

WHARTON, KA .

JOURNAL OF CELL BIOLOGY, 1982, 95 (01) :223-233

[5] KINETIC EVIDENCE FOR INSERTION OF ACTIN MONOMERS BETWEEN THE BARBED ENDS OF ACTIN-FILAMENTS AND BARBED END-BOUND INSERTIN, A PROTEIN PURIFIED FROM SMOOTH-MUSCLE [J].

RUHNAU, K ;

GAERTNER, A ;

WEGNER, A .

JOURNAL OF MOLECULAR BIOLOGY, 1989, 210 (01) :141-148

[6] POLARITY OF ACTIN AT LEADING-EDGE OF CULTURED-CELLS [J].

SMALL, JV ;

ISENBERG, G ;

CELIS, JE .

NATURE, 1978, 272 (5654) :638-639

[7] ACTIN-FILAMENTS ELONGATE FROM THEIR MEMBRANE-ASSOCIATED ENDS [J].

TILNEY, LG ;

BONDER, EM ;

DEROSIER, DJ .

JOURNAL OF CELL BIOLOGY, 1981, 90 (02) :485-494

[8] EXCHANGE OF ACTIN SUBUNITS AT THE LEADING-EDGE OF LIVING FIBROBLASTS - POSSIBLE ROLE OF TREADMILLING [J].

WANG, YL .

JOURNAL OF CELL BIOLOGY, 1985, 101 (02) :597-602

[9] STUDIES ON PROTEINS THAT COPURIFY WITH SMOOTH-MUSCLE VINCULIN - IDENTIFICATION OF IMMUNOLOGICALLY RELATED SPECIES IN FOCAL ADHESIONS OF NONMUSCLE AND Z-LINES OF MUSCLE-CELLS [J].

WILKINS, JA ;

RISINGER, MA ;

LIN, S .

JOURNAL OF CELL BIOLOGY, 1986, 103 (04) :1483-1494