REGULATION OF EXPRESSION OF MAJOR OUTER SURFACE-PROTEINS IN BORRELIA-BURGDORFERI

被引：52

作者：

MARGOLIS, N

ROSA, PA

机构：

来源：

INFECTION AND IMMUNITY | 1993年 / 61卷 / 05期

关键词：

D O I：

10.1128/IAI.61.5.2207-2210.1993

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We have characterized a Borrelia burgdorferi clone (CA-11 2A) that does not synthesize the major outer surface proteins, OspA and OspB. While the osp operon is intact and capable of expression, no mRNA transcript is detectable in this clone. These results suggest that osp operon expression in the B. burgdorferi clone can be regulated at the level of transcription.

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页码：2207 / 2210

页数：4

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