ELEVATED LEVELS OF SOLUBLE INTERLEUKIN-2 RECEPTORS IN TUBERCULOUS PLEURAL EFFUSIONS

被引：20

作者：

ITO, M ^{[1
]}

KOJIRO, N ^{[1
]}

SHIRASAKA, T ^{[1
]}

MORIWAKI, Y ^{[1
]}

TACHIBANA, I ^{[1
]}

KOKUBU, T ^{[1
]}

机构：

[1] OSAKA UNIV,SCH MED,DEPT INTERNAL MED 3,OSAKA,JAPAN

来源：

CHEST | 1990年 / 97卷 / 05期

关键词：

D O I：

10.1378/chest.97.5.1141

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculous pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patients with tuberculous pleurisy, the level of soluble IL-2R in pleural fluid was markedly greater than that in serum. Furthermore, a significant positive correlation was observed between soluble IL-2R levels and adenosine deaminase levels in tuberculous pleural fluid. These findings suggest that elevated levels of pleural fluid soluble IL-2R in tuberculous pleurisy could reflect the local proliferation of activated T-cells and may be clinically useful in the diagnostic procedures for patients with pleural tuberculosis.

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页码：1141 / 1143

页数：3

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