SYNTHESIS OF ALPHA-KETOLS MEDIATED BY DIVALENT SAMARIUM COMPOUNDS

被引：75

作者：

COLLIN, J ^{[1
]}

NAMY, JL ^{[1
]}

DALLEMER, F ^{[1
]}

KAGAN, HB ^{[1
]}

机构：

[1] UNIV PARIS 11,INST CHIM MOLEC ORSAY,SYNTHESE ASYMETR LAB,CNRS,URA 255,F-91405 ORSAY,FRANCE

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 09期

关键词：

D O I：

10.1021/jo00009a035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Coupling reactions of acid chlorides are mediated by SmI2 and SmCp2, leading to alpha-ketols 3. Condensation reactions of acid chlorides on aldehydes similarly product alpha-ketols 5; with ketones, best results are obtained with use of SmI2. Reactivities of SmI2 and SmCp2 are compared and mechanisms of the reactions discussed. Formation of an acylsamarium species is shown.

引用

页码：3118 / 3122

页数：5

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