COLOCALIZATION OF NGF RECEPTOR WITH VIP IN RAT SUPRACHIASMATIC NEURONS

被引：23

作者：

KISS, J

PATEL, AJ

HALASZ, B

机构：

[1] SEMMELWEIS UNIV MED,H-1094 BUDAPEST,HUNGARY

[2] NATL INST MED RES,DIV NEUROPHYSIOL & NEUROPHARMACOL,LONDON NW7 1AA,ENGLAND

来源：

NEUROREPORT | 1993年 / 4卷 / 12期

关键词：

NERVE GROWTH FACTOR RECEPTOR; COLOCALIZATION; SUPRACHIASMATIC NUCLEUS; VASOACTIVE INTESTINAL POLYPEPTIDE; IMMUNOCYTOCHEMISTRY; NEUROPEPTIDES;

D O I：

10.1097/00001756-199309150-00007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

LOW-AFFINITY nerve growth factor receptor (p75NGFR) and vasoactive intestinal polypeptide (VIP) immunoreactive neuronal structures and their interrelationship were investigated at light and electron microscopic levels in rat suprachiasmatic nucleus (SCN). p75NGFR immunoreactive neuronal perikarya were detected in the ventrolateral part, while the dorsolateral region contained mainly receptor positive fibres. Double-label immunocytochemistry showed that nearly all p75NGFR positive neurones in the ventrolateral region of the SCN also contained VIP. The axons of the receptor positive neurones terminated on unidentified neurones. In single-label experiments, the axons of the VIP containing neurones formed axodendritic synapses on cells containing the same peptide. The findings provide further insight on the chemical structural organization of the SCN.

引用

页码：1315 / 1318

页数：4

共 21 条

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