REGIOSELECTIVE O-DEMETHYLATION OF APORPHINES WITH METHANESULFONIC-ACID METHIONINE - AN EFFICIENT ONE-POT TRANSFORMATION OF THEBAINE TO (R)(-)-2-METHOXYAPOMORPHINE

被引：7

作者：

BERENYI, S

CSUTORAS, C

GYULAI, S

MAKLEIT, S

机构：

[1] Department of Organic Chemistry, Lajos Kossuth University, Debrecen, H-4010

来源：

SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1080/00397919508011359

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Methoxyapomorphine (4) was obtained by the rearrangement of thebaine (1) with methanesulfonic acid in the presence of methionine, a reagent system suitable for the regioselective O-demethylation of aporphine derivatives.

引用

页码：283 / 288

页数：6

共 5 条

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