CORRELATION OF IGG FC RECEPTORS ON GRANULOCYTES WITH SERUM IMMUNE-COMPLEX LEVEL IN SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：12

作者：

SZUCS, G

KAVAI, M

KISS, E

CSIPO, I

SZEGEDI, GY

机构：

[1] Third Department of Medicine, University Medical School of Debrecen, Debrecen

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1995年 / 42卷 / 05期

关键词：

D O I：

10.1111/j.1365-3083.1995.tb03699.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of Fc gamma RI, Fc gamma RII and Fc gamma RIII on granulocytes in the blood of patients with systemic lupus erythematosus was investigated. The relationship between the receptor expression and serum immune complex (IC) concentration was analysed. The decrease in mean fluorescence intensity of both Fc gamma RII and Fc gamma RIII of patients' granulocytes stained by specific monoclonal antibodies (using MoAb IV.3 and 3G8) was significant. The detected decrease of Fc gamma RII was inversely correlated with the high circulating IC level in patients' sera.

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页码：577 / 580

页数：4

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