EGG AND SOYA PHOSPHOLIPIDS - SONICATION AND DIALYSIS - A STUDY ON LIPOSOME CHARACTERIZATION

被引：15

作者：

MEMOLI, A

PALERMITI, LG

TRAVAGLI, V

ALHAIQUE, F

机构：

[1] UNIV SIENA,DIPARTIMENTO FARM CHIM TECNOL,I-53100 SIENA,ITALY

[2] UNIV CAGLIARI,DIPARTIMENTO FARM CHIM TECNOL,CAGLIARI,ITALY

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1995年 / 117卷 / 02期

关键词：

SMALL UNILAMELLAR VESICLES; EGG PHOSPHOLIPID; SOYA PHOSPHOLIPID; SONICATION; DIALYSIS;

D O I：

10.1016/0378-5173(94)00314-U

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Liposome-Triton X-100 interactions were studied by turbidity measurements and two detergent concentrations, corresponding to the maximum (i.e., detergent-saturated vesicles; R(sat)) and minimum (i.e., completely disruped liposomes; R(sol)) turbidity values, were identified. The tested liposomes (SUV) were prepared with phospholipids of different origin (egg and soya) and according to different methods (sonication and dialysis). The data obtained, together with size measurements carried out by electron microscopy, were related to the stability of the vesicles.

引用

页码：159 / 163

页数：5

共 11 条

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ANZAI K, 1980, CHEM PHARM BULL, V28, P1762

[2] SPECTROPHOTOMETRIC DETERMINATION OF BILE-ACIDS - AN EVALUATION [J].