SYNTHESIS OF L-6-[I-123]IODO-M-TYROSINE A POTENTIAL SPECT BRAIN IMAGING AGENT

被引:5
作者
ADAM, MJ [1 ]
PONCE, YZ [1 ]
BERRY, JM [1 ]
机构
[1] BRITISH COLUMBIA INST TECHNOL,BURNABY V5G 3H,BC,CANADA
关键词
D O I
10.1002/jlcr.2580280911
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
L‐6‐[123I]Iodo‐m‐tyrosine was synthesized by the direct iodination of L‐m‐tyrosine with [123I]‐NaI and Chloramine‐T. The product was purified by reverse phase HPLC to give the final product in 57% radiochemical yield with a radiochemical purity of greater than 97%. Copyright © 1990 John Wiley & Sons, Ltd.
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收藏
页码:1065 / 1072
页数:8
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