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HEMOLYTIC-ACTIVITY OF THE PASTEURELLA-HAEMOLYTICA LEUKOTOXIN
被引：59
作者：
MURPHY, GL
WHITWORTH, LC
CLINKENBEARD, KD
CLINKENBEARD, PA
机构：
关键词：
D O I：
10.1128/IAI.63.8.3209-3212.1995
中图分类号：
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A Pasteurella haemolytica mutant incapable of producing leukotoxin was created by allelic replacement, Concentrated culture supernatants from wild-type P. haemolytica, but not from the mutant, contained the 102-kDa leukotoxin protein and lysed bovine lymphoma cells and sheep erythrocytes. Wild-type P. haemolytica demonstrated the typical beta-hemolytic phenotype on sheep and rabbit blood agar, whereas the mutant did not.
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页码：3209 / 3212
页数：4
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