COMBINED-MODALITY TREATMENT OF ADDUCTOR SPASMODIC DYSPHONIA WITH BOTULINUM TOXIN AND VOICE THERAPY

被引:59
作者
MURRY, T
WOODSON, GE
机构
[1] University of Pittsburgh, Pittsburgh, PA
[2] Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Tennessee, Memphis, TN
关键词
BOTULINUM TOXIN; ADDUCTOR SPASMODIC DYSPHONIA; COMBINED MODALITY;
D O I
10.1016/S0892-1997(05)80211-5
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
A combined-modality treatment program consisting of botulinum toxin injection (Botox) and voice therapy was used to treat 17 subjects diagnosed with adductor spasmodic dysphonia (ADD SD). Ten subjects with ADD SD served as the control and were given Botox only. Voice therapy after Botox injection was directed toward reducing the hyperfunctional vocal behaviors, primarily glottal overpressure at voice onset and anterior-posterior squeezing. The results indicated that subjects who underwent combined-modality treatment maintained significantly higher mean airflow rates for significantly longer periods. Moreover, there was a carryover effect in these patients when they received Botox only. Adductor spasmodic dysphonia is treated most effectively when intrinsic laryngeal muscle spasms are reduced or eliminated by Botox injection and extrinsic hyperfunctional vocal behaviors are treated with voice therapy.
引用
收藏
页码:460 / 465
页数:6
相关论文
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