2-AMINOBENZOYL-PEPTIDE-2,4-DINITROANILINOETHYLAMIDES - FACILE FLUORESCENT DETECTION SYSTEM FOR SEQUENCE SPECIFIC PROTEASES

被引:15
作者
NISHINO, N
MAKINOSE, Y
FUJIMOTO, T
机构
关键词
D O I
10.1246/cl.1992.77
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
New fluorogenic peptides with efficient quenching group were synthesized and subjected to the action of thermolysin and trypsin. The hydrolysis of the peptide bond resulted in the increase in fluorescence intensity by 50-200-fold of the quenched peptides.
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页码:77 / 80
页数:4
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