CIRCULATING TRANSFERRIN RECEPTOR IN HUMAN-SERUM

被引:167
作者
KOHGO, Y
NISHISATO, T
KONDO, H
TSUSHIMA, N
NIITSU, Y
URUSHIZAKI, I
机构
关键词
D O I
10.1111/j.1365-2141.1986.tb04120.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Circulating transferrin receptor has been detected in human serum with a sensitive immunoassay. The mean concentrations of the serum transferrin receptor in healthy males and females were 251 .+-. 94 (mean .+-. SD) ng/ml and 256 .+-. 99 ng/ml, respectively. The serum receptor concentration in patients with haematological malignancies, including acute leukaemia, mutliply myeloma and malignant lymphoma, varied widely, from normal to 1100 ng/ml. A single band with an approximate molecular weight between 80,000 and 100,000 daltons was obtained by polyacrylamide gel electrophoresis-immunoblotting analysis of serum.
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页码:277 / 281
页数:5
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