ALUMINA-MEDIATED DEACETYLATION OF BENZALDEHYDE DIACETATES - A SIMPLE DEPROTECTION METHOD

被引：136

作者：

VARMA, RS

CHATTERJEE, AK

VARMA, M

机构：

[1] The Center for Biotechnology, Baylor College of Medicine, The Woodlands, TX 77381

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 20期

关键词：

DEPROTECTION; ARYLALDEHYDE DIACETATES; SOLID SURFACE; ALUMINA; SELECTIVITY; MICROWAVE IRRADIATION;

D O I：

10.1016/S0040-4039(00)73662-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, extremely fast, and high yielding method for the selective deprotection of benzaldehyde diacetates is described which occurs under mild conditions on neutral alumina surface. Gentle heating, using microwave irradiation or conventional methods facilitates the procedure.

引用

页码：3207 / 3210

页数：4

共 30 条

[1]

Abramovich R. A, 1991, ORG PREP P INT, V23, P683

[2] MICROWAVE-INDUCED ORGANIC-REACTION ENHANCEMENT CHEMISTRY .4. CONVENIENT SYNTHESIS OF ENANTIOPURE ALPHA-HYDROXY-BETA-LACTAMS [J].