CONVENIENT AND REGIOSELECTIVE SYNTHESES OF 3,4-DISUBSTITUTED DELTA-3-PYRROLIN-2-ONE DERIVATIVES STARTING FROM 2-TOSYL-3,4-DISUBSTITUTED PYRROLES

被引：40

作者：

KINOSHITA, H

HAYASHI, Y

MURATA, Y

INOMATA, K

机构：

来源：

CHEMISTRY LETTERS | 1993年 / 08期

关键词：

D O I：

10.1246/cl.1993.1437

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3,4-Disubstituted DELTA3-pyrrolin-2-ones were prepared in high yields via 5-tosyl-DELTA3-pyrrolin-2-ones (4) starting from 2-tosylpyrroles regioselectively. The compounds 4 were found to be useful intermediates for the preparation of a variety of DELTA3-pyrrolin-2-one derivatives. The reactions of 4 with various nucleophiles and active methylene compounds bearing an appropriate leaving group are described.

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页码：1437 / 1440

页数：4

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