BACILLUS-CALMETTE-GUERIN IN THE TREATMENT OF STAGE T1 GRADE-3 TRANSITIONAL-CELL CARCINOMA OF THE BLADDER - LONG-TERM RESULTS

被引：74

作者：

PANSADORO, V ^{[1
]}

EMILIOZZI, P ^{[1
]}

DEFIDIO, L ^{[1
]}

DONADIO, D ^{[1
]}

FLORIO, A ^{[1
]}

MAURELLI, S ^{[1
]}

LAURETTI, S ^{[1
]}

STERNBERG, CN ^{[1
]}

机构：

[1] SAN CAMILLO HOSP, DEPT UROL, ROME, ITALY

来源：

JOURNAL OF UROLOGY | 1995年 / 154卷 / 06期

关键词：

BLADDER; CARCINOMA; TRANSITIONAL CELL; MYCOBACTERIUM BOVIS;

D O I：

10.1016/S0022-5347(01)66692-8

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: We performed a retrospective long-term study to evaluate the results Materials and Methods: Between 1981 and 1993, 593 patients with superficial transitional cell carcinoma of the bladder underwent transurethral resection. Of 64 patients with stage T1 grade 3 disease 50 received intravesical bacillus Calmette-Guerin after transurethral resection of all visible tumor. Results: At a median followup of 42 months (range 12 to 112) 36 patients (72%) are disease-free and have not required further treatment. Superficial recurrence was noted in 8 patients (16%). Disease progressed in 6 patients (12%), including 5 with locally invasive and 1 with metastatic disease. Cystectomy was performed for progression in 4 patients and for recurrent stage T1 grade 3 disease in 1. There was 1 disease related death (2%). The overall survival rate is 94%. Conclusions: Intravesical bacillus Calmette-Guerin appears to be the most effective conservative treatment for patients with stage T1 grade 3 bladder cancer.

引用

页码：2054 / 2058

页数：5

共 43 条

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