GLUCOCORTICOIDS IN CANCER-THERAPY

被引：54

作者：

COLEMAN, RE

机构：

[1] Department of Clinical Oncology, Weston Park Hospital, Sheffield

来源：

BIOTHERAPY | 1992年 / 4卷 / 01期

关键词：

CANCER CHEMOTHERAPY; GLUCOCORTICOIDS; PREDNISOLONE;

D O I：

10.1007/BF02171708

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Glucocorticoids are often included with other agents in cancer treatment although the mode of action is not clear. They are useful in the primary combination chemotherapy of both acute and chronic lymphocytic leukaemias, Hodgkins' and non-Hodgkin's lymphomas, multiple myeloma and breast cancer. Other uses for glucocorticoids in cancer patients include an anti-inflammatory action for the oedema of cranial and spinal metastases, a weak antihypercalcaemic effect and the ability to suppress tumour-related fever.

引用

页码：37 / 44

页数：8

共 54 条

[1]

ALEXANIAN R, 1986, ANN INTERN MED, V105, P8, DOI 10.7326/0003-4819-105-1-8

[2]

DIFFERENCES IN CEREBROSPINAL-FLUID PENETRATION OF CORTICOSTEROIDS - POSSIBLE RELATIONSHIP TO THE PREVENTION OF MENINGEAL LEUKEMIA [J].