Interaction of carcinogenic chromium(VI) oxide, CrO3, with main nonenzymatic cellular reductants at physiological conditions. Electronic spectra and magnetic studies

The interaction of CrO3 with ascorbic acid, glutathione and cysteine at physiological conditions (pH=7.4, t=37 degrees C) was investigated using spectral (diffuse reflectance spectra) and magnetic methods. The obtained powders appeared to be Cr(III) complexes of the [Cr(A, B)(H2O)(x)](n-) type, where A, B are organic ligands (A-ascorbic acid, B-glutathione or cysteine). The spectral resolution of the bands enhanced with a digital filter method revealed the lowering symmetry effect in the chromium(III) coordination sphere. The comparison of the results obtained for K2CrO4 with these studied in the present paper was made.